All cause mortality		Febrile episodes		Clinically documented infections		Adverse events
Comparison	RR (95 % Cl)	Studies (patients)	RR (95 % Cl)	Studies (patients)	RR (95 % Cl)	Studies (patients)	RR (95 % Cl)	Studies (patients)
Quinolones vs. TMP – SMZ	1.07 (0.66–0.72)	10 (917)	0.95 (0.86–1.04)	10 (931)	1.33 (1.06–1.66)	10 (931)	0.74 (0.63–0.87)	10 (1027)
Quinolones plus GP vs. quinolones	1.23 (0.66–2.30)	9 (1232)	1.05 (0.98–1.12)	8 (1133)	1.01 (0.79–1.30)	7 (1093)	1.94 (1.28–2.94)	6 (516)
Non-absorbable vs. systemic	1.06 (0.74–1.50)	8 (813)	1.06 (1.00–1.13)	8 (808)	1.11 (0.95–1.31)	10 (862)	1.23 (1.01–1.50)	10 (934)
Systemic plus non-absorbable vs. systematic	0.9 (0.34–2.38)	2 (83)	0.93 (0.72–1.20)	2 (103)	0.54 (0.25–1.15)	1 (63)	1.75 (1.02–3.00)	3 (146)