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. Author manuscript; available in PMC: 2021 Mar 16.
Published in final edited form as: Behav Brain Res. 2020 Jan 8;382:112454. doi: 10.1016/j.bbr.2019.112454

Figure 3. Tactile recognition memory impaired by HFD.

Figure 3.

A) The percentage of time spent exploring the familiar and novel sandpaper grit and B) total exploration time of mice following 30-33 weeks of diet on either the standard diet (STD) or the high-fat diet (HFD) during novel tactile recognition (NTR). The dashed line represents 50% exploration; n= 7 and 8 for the STD and HFD groups, respectively. C) Discrimination index from corner test to distinguish the direction in which mice turn when approaching a corner following unilateral and bilateral whisker trim, and after 6 months of re-growth. The dashed line represents a discrimination index value of 0; data represented as mean and standard error of the mean (SEM); n= 9 and 12 in the STD and HFD groups, respectively; **p<0.01.