| Post-therapy clinical cure rates, % (n/N) |
||||
|---|---|---|---|---|
| Population | TEL | COMP | Difference [95% Cl] | p-value |
| mITT (investigator's analysis) | 86.0% (208/242) | 78.8% (189/240) | [0.004, 0.140] | 0.04 |
| mITT (blinded experts' analysis))a | 92.1% (223/242) | 85.8% (206/240) | [0.008, 0.119] | 0.03 |
| PP (investigator's analysis) | 87.2% (191/219) | 79.9% (175/219) | [0.004, 0.142] | 0.05 |
| PP (blinded experts' analysis)a | 94.1% (206/219) | 87.7% (192/219) | [0.010, 0.118] | 0.03 |
a
Clinical failure = subsequent antibiotic for lower respiratory tract infection or CAP-related fever post-therapy.