Bioavailability (AUC %)
Study	N	Drug (mg)	Duration (d)	POS (mg)	POS	Concomitant Drug
1	12	Cimetidine (800)	10	200 qd	61	ND
2	4	Cyclosporine (ED)	SS	200 qd	ND	Doses reduced −14-29% in 3 of 4
3	12	Glipizide(10)	1	400 bid	91	118
4	36	Phenytoin (200)	10	200 qd	50	115
5	24	Rifabutin (300)	17	200 qd	51	172
6	34	Tacrolimus (0.05a)	1	400 bid	ND	458
7	17	Zidovudine (600)	SS	200 qd	ND	112
	17	Lamivudine (300)	SS	200 qd	ND	107
	17	Ritonavir (1200)	SS	200 qd	ND	130
	17	Indinavir (3200)	SS	200 qd	ND	116

ND = not determined.

^amg/kg;