Table 1.
Infectious agents detected in otherwise healthy infants hospitalized for a first episode of wheezing
| Infections | Age | |
|---|---|---|
| <3 months (n = 53) | 3–12 months (n = 32) | |
| Patients infected with a single pathogen, no. (%) | 38 (71.8)a | 23 (71.8) |
| RSV, no. (%) | 30 (56.6)b,c | 22 (68.7)c |
| Influenza viruses, no. (%) | 3 (5.7) | 0 (0.0) |
| hCoVs, no. (%) | 3 (5.7) | 0 (0.0) |
| hMPV, no. (%) | 1 (1.9) | 0 (0.0) |
| Bocavirus, no. (%) | 1 (1.9) | 0 (0.0) |
| Mycoplasma pneumoniae, no. (%) | 0 (0.0) | 1 (3.1) |
| Patients infected with more than one pathogen, no. (%) | 8 (15.1) | 7 (21.9) |
| RSV + hCoVs, no. (%) | 2 (3.7) | 1 (3.1) |
| RSV + adenovirus, no. (%) | 0 (0.0) | 2 (6.3) |
| RSV + paraechovirus, no. (%) | 0 (0.0) | 2 (6.3) |
| RSV + influenza viruses, no. (%) | 1 (1.9) | 1 (3.1) |
| RSV + rhinovirus, no. (%) | 1 (1.9) | 1 (3.1) |
| Rhinovirus + enterovirus, no. (%) | 1 (1.9) | 0 (0.0) |
| Rhinovirus + parainfluenza virus, no. (%) | 1 (1.9) | 0 (0.0) |
| Influenza + adenovirus, no. (%) | 1 (1.9) | 0 (0.0) |
| Influenza + bocavirus, no. (%) | 1 (1.9) | 0 (0.0) |
| Patients not infected with any of the studied pathogens, no. (%) | 7 (13.2) | 2 (6.2) |
RSV, respiratory syncytial virus; hCoVs, human coronaviruses; hMPV, human metapneumovirus.
ap <0.0001 vs. patients infected with more than one pathogen and vs. patients not infected with any of the studied pathogens.
bp <0.05 vs. RSV in infants aged 3–12 months.
cp <0.0001 vs. patients infected with a single pathogen other than RSV.