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. 2020 Mar 13;8(1):e20.

Table 3.

Screening performance characteristics of different scoring systems in prediction of acute appendicitis in emergency department

Alvarado Ohmann RIPASA Tzanakis Eskelinen
TP 40 47 55 56 42
TN 8 8 8 8 7
FP 1 1 1 1 2
FN 25 18 10 9 23
Sensitivity 60.9
(48.64-73.35)
71.9
(59.81-82.69)
75
(64.81-86.47)
84.4
(75.34-93.47)
64.1
(51.77-76.08)
Specificity 89.9
(51.75-99.72)
89.9
(51.75-99.72)
99.72
(51.75-100)
99.88
(51.75-99.72)
78
(39.99-99.19)
PPV 97.56
(86.19-99.61)
97.92
(88.04-99.67)
98.04
(88.69-99.69)
98.25
(89.80-99.72)
95.45
(85.93-98.63)
NPV 24.24
(17.89-31.98)
30.77
(21.98-41.21)
34.78
(24.44-46.80)
47.06
(31.72-62.97)
23.33
(15.86-32.96)
PLR 5.54
(0.86-35.56)
6.51
(1.02-41.55)
6.92
(1.09-44.15)
7.75
(1.22-49.24)
2.91
(0.85-10.00)
NLR 0.43
(0.29-0.64)
0.21
(0.20-0.49)
0.26
(0.16-0.43)
0.16
(0.08-0.30)
0.45
(0.28-0.73)
AUC 0.93
(0.87-0.99)
0.94
(0.88-1.00)
0.89
(0.81-0.97)
0.96
(0.90-1.00)
0.86
(0.77-0.97)

Data are presented with 95% confidence interval (CI). Measures are calculated in cut-offs: ≥8 for Alvarado score; ≥12 for Ohmann score; ≥12 for RIPASA score; ≥8 for Tzanakis score; ≥57 for Eskelinen score.

TP: true positive; TN: true negative; FP: false positive; FN: false negative; PPV: positive predictive value; NPV: negative predictive value; PLR: positive likelihood ratio; Negative likelihood ratio; AUC; area under the receiver operating characteristic (ROC) curve.