Table 1.

Characteristics of included studies

Author; year; Country	Study type	Setting of patients	Age	No. AKI; non-AKI	No. boys	AKI definition	AKI severity	RAI time; cut-offs	Follow up	TP	FP	TN	FN
Basu, Cohort 1; 2014; USA	RCS	Sepsis	0.2 to 12.5	28; 116	83	KDIGO	Severe	0; 8	3	21	31	85	7
Basu, Cohort 2; 2014; Canada	RCS	ICU admitted	0.2 to 12.5	12; 106	74	KDIGO	Severe	0; 8	3	7	11	95	5
Basu, Cohort 3; 2014; Canada	PCS	ICU admitted	0.2 to 12.5	11; 97	64	KDIGO	Severe	0; 8	3	10	27	70	1
Basu, Cohort 4; 2014; USA	PCS	ICU admitted	0.2 to 12.5	29; 185	134	KDIGO	Severe	0; 8	3	27	118	67	2
Basu; 2018; Multicenter	PCS	ICU admitted	2 to 14.5	553; 1037	882	KDIGO	Severe	0; 8	3	121	165	1057	247
Gawada; 2019; India	PCS	ICU admitted	0.1 to 12	114; 48	95	KDIGO	Severe	0; 8	3	62	24	74	2
Hanson; 2020; USA	PCS	ICU admitted	0.1 to 25	17; 64	38	KDIGO	Any AKI	0; 8	in-hospital	16	10	54	1
Kaur; 2018; India	PCS	ICU admitted	0.1 to 18	53; 360	301	KDIGO	Severe	0; 8	3	25	44	336	8
Menon; 2016; USA	PCS	ICU admitted	0.2 to 25	15; 141	98	KDIGO	Severe	0; 8	3	12	40	101	3
Perez; 2018; Philippine	RCS	Sepsis	<19	90; 132	130	NR	NR	0; 8	3	87	8	124	3
Sethi; 2018; India	PCS	ICU admitted	6.5 ± 5.9 months	33; 69	69	KDIGO	Severe	0; 8	3	27	21	48	6
Sundararaju; 2019; India	PCS	ICU admitted	0.1 to 18	29/256	189	KDIGO	Severe	0; 8	3	24	117	139	5
Youssef; 2019; Egypt	PCS	ICU admitted	0.2 to 14	13; 40	34	pRIFLE	Severe	0; 8	3	10	1	39	3
Zeid; 2019; Egypt	PCS	ICU admitted	0.2 to 7	10; 43	45	pRIFLE	Severe	0; 8	3	9	16	27	1

AKI: Acute kidney injury; FN: False negative; FP: False positive; KDIGO: Kidney Disease Improving Global Outcomes; NR: Not reported; PCS: Prospective cohort study; pRIFLE: Pediatric Risk, Injury, Failure, Loss, End Stage Renal Disease; RCS: Retrospective cohort study; TN: True negative; TP: True positive; ICU: Intensive care unit.