Figure 2.

RP11‐81H3.2 knockdown inhibits the proliferation, migration, and invasion of GC cells. A, SGC‐790 1 and BGC‐823 cells were transfected with RP11‐81H3.2 knockdown vector (sh‐RP11‐81H3.2) or negative control vector (sh‐NC). The knockdown efficiency was examined by qPCR. B, C, The cell proliferation of SGC‐7901 and BGC‐823 cells transfected with sh‐RP11‐81H3.2 or sh‐NC was assessed by CCK‐8 kit at indicated time points. D‐E, The apoptosis of cells with knockdown RP11‐909N7.2 was determined by the flow cytometry. F‐G, The cell invasion capability of SGC‐7901 and BGC‐823 cells transfected with sh‐RP11‐81H3.2 or sh‐NC was analyzed by transwell assay. (H‐I) Cell migration capability of SGC‐7901 and BGC‐823 cells transfected with sh‐RP11‐81H3.2 or sh‐NC was analyzed by wound healing assay.*P < .05, **P < .01, compared with sh‐NC group