Figure 4.

Overexpression of miR‐339 inhibits the proliferation, migration, and invasion of GC cells, and enhances GC cell apoptosis. A, SGC‐7901 and BGC‐823 cells were transfected with miR‐339 mimic or negative control vector (miR‐NC). The relative expression of miR‐339 was examined by qPCR. B, C, The cell proliferation of SGC‐7901 and BGC‐823 cells transfected with miR‐NC or miR‐339 mimic was assessed by MTT assay at indicated time points. D, E, The cell invasion capability of SGC‐7901 or BGC‐823 cells transfected with miR‐NC or miR‐339 mimic was analyzed by transwell assay. F, G, The cell migration capability of SGC‐7901 and BGC‐823 cells transfected with miR‐NC or miR‐339 mimic was analyzed by wound healing assay. H, I, The apoptosis of GC cells were determined by the flow cytometry. ** P < .01 compared with miR‐NC group