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Main results of PEMBREIZH, KEYNOTE‐024 and KEYNOTE‐042
| Parameter | PEMBREIZH | KEYNOTE‐0244, 20 |
KEYNOTE‐042 (TPS ≥50% subgroup)16 |
|---|---|---|---|
| PFS | 10,1 mo 95% CI [8,8 to NA] | 10.3 mo 95% CI [6,7 to NA] | 7,1 mo 95% CI [5,9 to 9,0] |
| OS | 15,2 mo 95% CI [13,9 to NA] | 30,0 mo 95% CI [18,3 to NA] | 20,0 mo 95% CI [15,4 to 24,9] |
| ORR | 53,7% | 44,8% | 39% |
| IrAEs * | 8% | 9,7% | 8% |
Abbreviations: IrAEs: immune‐related adverse events; ORR: Objective response rate; OS: Overall survival; PFS: Progression‐free survival
