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. Author manuscript; available in PMC: 2020 Sep 9.
Published in final edited form as: Nat Neurosci. 2020 Mar 9;23(4):583–593. doi: 10.1038/s41593-020-0603-0

Fig. 2. Spatiotemporal dynamics of brain disorder risk genes.

Fig. 2.

a. Heritability enrichment of brain disorders in active regulatory elements of the fetal and adult brain. Enrichment ± standard error (circle) and significance of heritability enrichment (triangle) are depicted. b-c. Developmental expression trajectories of brain disorder risk genes. PCW, post-conception week; M, month; Y, year. (Left) N = 410 and 453 for prenatal and postnatal samples, respectively. Center, median; box = 1st-3rd quartiles (Q); minima, Q1 – 1.5 x interquartile range (IQR); maxima, Q3 + 1.5 x IQR. (Right) LOESS smooth curve with 95% confidence bands.

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