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Quercetin activates SIRT1 and inhibits NLRP3 inflammasome activation in the brain of db/db mice. Representative Western blots A, results of protein expression in the brain of db/db mice. B, SIRT1. C, NLRP3. D, ASC. E, IL‐18. F, Cleaved Caspase‐1. G, IL‐1β. db/db + QL: Quercetin (35 mg/kg/d); db/db + QH: Quercetin (70 mg/kg/d). Data represent mean ± SEM (n = 8 per group). # P < .05, ## P < .01, ### P < .001 vs db/m; *P < .05, **P < .01, ***P < .001 vs db/db
