Table 1.
Characteristics of study population by group
| PHIV (n = 40) | PING (n = 80) | p-value | |
|---|---|---|---|
| Female (n(%)) | 21 (53%) | 40 (50%) | 0.80 |
| Age (mean (SD)) | 16.7 (2.4) | 16.3 (2.8) | 0.66 |
| Race (n(%)) | 0.44 | ||
| Black | 29 (73%) | 52 (65%) | |
| White | 10 (25%) | 28 (35%) | |
| Hispanic ethnicity (n(%)) | 5 (13%) | 10 (13%) | 1.00 |
| Caretaker education (n(%))a | 0.35 | ||
| Less than high school | 7 (18%) | 8 (10%) | |
| High School or GED | 13 (33%) | 28 (35%) | |
| Some college or 2 year degree | 10 (25%) | 25 (31%) | |
| 4 year college | 3 (7.5%) | 12 (15%) | |
| Graduate School | 7 (18%) | 7 (8.8%) | |
| Annual household income (n(%))b | 0.52 | ||
| Less than 10000 | 2 (5%) | 5(6.3%) | |
| 10001–20000 | 10 (25%) | 11 (14%) | |
| 20001–30000 | 6 (15%) | 14 (18%) | |
| 30001–40000 | 6 (15%) | 14 (18%) | |
| 40001–50000 | 3 (7.5%) | 3 (3.8%) | |
| 50001–100000 | 11 (28%) | 21 (26%) | |
| greater than 100000 | 2 (5%) | 12 (15%) | |
| HIV disease-severity measures (median (Q1, Q3) or N (%) for PHIV | |||
| CD4% < 15% | 17 (43%) | ||
| Nadir CD4% | 16.5 (8.0,23.8) | ||
| Age (years) at nadir CD4% | 5.7 (2.2,10.9) | ||
| Nadir CD4 count | 236.0 (112.0, 392.5) | ||
| Age (years) at nadir CD4 count | 8.2 (3.8, 11.6) | ||
| Most recent* CD4 count | 627 (453.0, 846.0) | ||
| Most recent* CD4% | 35.9 (27.6,42.9) | ||
| Age (years) at most recent CD4%/CD4 count | 17.0 (14.9,18.2) | ||
| Log peak HIV RNA viral load (copies/mL) | 5.7 (5.2,5.9) | ||
| Age (years) at peak RNA | 2.5 (0.6,5.3) | ||
| Most recent* RNA count > 400 copies/mL | 6 (15) | ||
| Age (years) at most recent RNA | 17.0 (14.9, 18.2) | ||
| % of viral load > 1000 copies/mL in past 5 years | 6.5 (0.0, 29.0) | ||
| Age at start of cART | 3.5 (1.4 -6.3) | ||
| ARV regimen at the time of scan | |||
| cART | 37(92%) | ||
| Not on cART | 1 (3%) | ||
| Not on any antiretrovirals | 2 (5%) | ||
| CDC ‘C’ Classification | 9 (22%) | ||
GED = General Education Development test passed.
Cart = combination antiretrovial therapy (regimen including at least 3 drugs from at least 2 drug classes).
CDC = Centers for Disease Control.
⁎
Most recent = closest clinical data to neuroimaging scan.
a
One missing value of PING subjects imputed.
b
Eleven missing values of PING subjects imputed.