Figure 2.

Upregulation of Specific Glycolytic Intermediates

(A–K) Various metabolites involved in the glycolysis and pentose phosphate pathway were analyzed from neural retina and RPE-choroid. The levels of these metabolites for both neural retina and RPE-choroid are shown (A–J) along with a graphical representation of glycolysis (K), with the significantly elevated metabolites in RPE-choroid boxed in red, those elevated in neural retina marked by an underline, and those not measured marked by an asterisk. Each group has a sample size of n = 8 for neural retina and n = 9 for RPE-choroid. The metabolites having significant differences between neural retina and RPE-choroid are shown (A–G) with ∗∗p<0.001, ∗∗∗p<0.0001, and ∗∗∗∗p<0.00001. Data presented as mean ± SEM. (NR, neural retina; RPE-Ch, RPE-choroid).