Figure 2.

Rab25 Is Linked with Poor Prognosis and Less Responsiveness of Patients with NPC to Radiotherapy

(A) RT responsiveness of 101 patients with NPC was correlated with Rab25 expression levels; clinic response of all patients was scored as complete response (CR), partial response (PR), and stable disease (SD), and expression levels of Rab25 were scored with four levels (0–4) illustrated in left. Scale bar, 50 μm. (B) Elevated Rab25 expression in a large scale of human cancers (red) compared with normal tissues (gray). The graph was generated from the GEPIA website (http://gepia.cancer-pku.cn/) and was based on the transcriptional level of Rab25 in an array of human cancer from multiple cohorts of TCGA study. The median expression of Rab 25 presented as transcripts per million (TPM) was chosen in each cancer type, and the case number of each cancer type was illustrated in Table S2. Right, Rab25 expression summarized from 483 patients with LUAD and 347 normal lung tissues (mean ± SD, ∗p < 0.05). (C) Overall survival or (D) disease-free survival of patients with LUAD generated using the log rank test based on Rab25 expression in LUAD tissues from the TCGA cohort.