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A
The social interaction time of control mice after knocking down CD39 (n = 10, 13 mice; Interaction F
1,42 = 0.1334, P = 0.7167; Group F
1,42 = 4.366, P = 0.0428; Drug F
1,42 = 0.002565, P = 0.9598, two‐way ANOVA with Tukey's post‐test).
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B
The locomotor activity of mice with LV‐siCD39 infusion into hippocampus in the open field test (n = 15, 13, 15, 14 mice; Interaction F
1,53 = 0.09372, P = 0.7607; Group F
1,53 = 0.1669, P = 0.6845; Drug F
1,53 = 1.450, P = 0.2339, two‐way ANOVA with Tukey's post‐test).
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C
The ATPase activity of control mice with LV‐ siCD39 intra‐hippocampal infusion (n = 9, 8 mice; P = 0.043, Student's t‐test).
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D
The ATP level of control mice with LV‐siCD39 intra‐hippocampal infusion (n = 4, 5 mice; P = 0.2181, Student's t‐test).
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E
The center distance of stressed mice with LV‐siCD39 in the OFT (n = 8, 11, 11 mice; Treatment, F
2,27 = 0.6317, P = 0.5394, one‐way ANOVA with Fisher's LSD test).
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F, G
Time spent in the open arms (F) and closed arms (G) of stressed mice with LV‐siCD39 in EPM test (n = 7, 12, 11 mice; for open arms, Treatment, F
2,27 = 3.650, P = 0.0395; CSDS – LV‐GFP versus Ctrl – LV‐GFP, P = 0.0183; for closed arms, Treatment, F
2,27 = 0.5164, P = 0.6024, one‐way ANOVA with Fisher's LSD test).
Data information: Data are expressed as the means ± SEM. *
< 0.05.
