Figure 1.

Schematic describing the timeline of the experimental set-up. Rats in each group were pretreated with samples or solvent by gavage administration for 7 days, once a day. On day 8, rats were anesthetized to prepare the ischemia/reperfusion model. The left anterior descending branch was ligated (successful surgery was confirmed by observing the cyanosis around the remote end of myocardium and ST-segment elevation and tall T-waves in ECG), after 30 min of ligation, 2 h of reperfusion was initiated by removing the ligation line.