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Fisetin reduces apoptosis of cardiomyocytes (A) Flow cytometry analysis with Annexin V-FITC/PI staining. (B) Quantification of cardiomyocyte apoptosis rate in UR quadrant (upper right quadrant). Fisetin (15 or 45 mg/kg) significantly decreased the percentage of apoptotic cardiomyocytes, compared with the model group. Fisetin inhibited apoptosis of myocardial cells in a dose dependent manner. *P<0.05 and **P<0.01 vs. model group. FITC, fluorescein isothiocyanate; PI, propidium iodide.
