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. 2020 Mar 9;19(5):3247–3258. doi: 10.3892/etm.2020.8586

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Copyright: © Qian et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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MAPK phosphorylation in CD14⁺ monocytes from patients with SR or SS asthma. (A) Plots of p-p38 MAPK MFI in gated CD14⁺ monocytes. (B) p-p38 MAPK MFI in CD14⁺ monocytes from patients with SR or SS asthma. Correlations between p-p38 MAPK MFI and (C) IL-35 level, (D) predicted FEV1%, (E) log(DEX-IC₅₀) and (F) E_max were analyzed by Spearman correlation test. Statistical significance was analyzed by Mann-Whitney U test. DEX, dexamethasone; DEX-IC₅₀, half-maximal inhibitory concentration of DEX; E_max, percentage inhibition at maximal concentration; IL, interleukin; FEV1, forced expiratory volume in 1 sec; SR, steroid-resistant; SS, steroid-sensitive; p-p38 MAPK, phosphorylated P38 mitogen activated kinase; MFI, mean fluorescence intensity.