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. 2020 Mar 12;19(5):3355–3361. doi: 10.3892/etm.2020.8600

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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circRNA_101951 is upregulated in both CRC clinical specimens and cell lines. (A) The GEO dataset (GSE126094) showed that circRNA_101951 was significantly upregulated in tumor samples compared with normal samples. (B) circRNA_101951 expression levels were examined using RT-qPCR in CRC samples and normal samples. (C) Kaplan-Meier survival analysis. (D) circRNA_101951 were examined using RT-qPCR in the CRC cell lines HT-29, HCT116, SW620 and SW480 and the normal colonic epithelial cells NCM460. The data shown represents the mean ± standard deviation (n=3). ^**P<0.01, ^***P<0.001 vs. the NCM460 cells. circRNA, circular RNA; CRC, colorectal cancer; KIF3a, kinesin II family member 3A; RT-qPCR, reverse transcription-quantitative PCR.