Figure 2.
circRNA_101951 exerted a tumor-promotive function in colorectal cancer. si-RNA targeting circRNA_101951 was transfected in SW480 cells. (A) circRNA_101951 expression levels were examined after transfection in SW480 cells using reverse transcription-quantitative PCR. (B) MTT assays were performed to examine the cell viability of SW480 cells after transfections. (C) Colony formation assays were performed to examine the clone ability of SW480 cells after transfection. (D) Flow cytometric analysis were performed to examine cell apoptosis of SW480 cells after transfection. (E) Flow cytometric analyses were performed to examine cell cycle progression of SW480 cells after transfection. The data shown represent the mean ± standard deviation (n=3). ***P<0.001 vs. the si-NC group. circRNA, circular RNA; OD, optical density; si-NC, negative control small interfering RNA; si-RNA, small interfering RNA.