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. 2014 Nov 26;113(4):1085–1099. doi: 10.1152/jn.00761.2014

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Fig. 8. — Lepr^db/db mice do not show signs of RPE permeability or overt structural damage even at late ages. A: representative photomicrographs from scanning laser ophthalmoscopy (SLO) imaging and spectral domain optical coherence tomography (OCT) of BKS.Lepr^+/+,db/+ (top) and BKS.Lepr^db/db mice (bottom) at 16 wk of age. B: representative photomicrographs from SLO imaging and OCT of B6.BKS.Lepr^+/+,db/+ (top) and B6.BKS.Lepr^db/db mice (bottom) at 50 wk of age. No overt structural damage to the retina or RPE is observed in either strain. IRDF, infrared darkfield; RFDF, red free dark field; AF, autofluorescence. Arrowheads indicate abnormal patterning observed.