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. Author manuscript; available in PMC: 2020 Jul 24.
Published in final edited form as: AAPS J. 2019 Jul 24;21(5):93. doi: 10.1208/s12248-019-0362-6

Fig. 2.

Fig. 2.

Digitized mean TOF concentration-time data following the indicated doses in healthy rats, mice, and humans and their jointly fitting profiles across species based on the mPBPK model (Fig. I). Parameters utilized and estimates are listed in Table I