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. 2020 Feb 27;21(4):e49075. doi: 10.15252/embr.201949075

Figure 2. Myeloid‐specific Cripto deletion perturbs MP plasticity without affecting monocyte/macrophage accumulation.

Figure 2

  • A
    Representative pictures of immunostaining for F4/80 (green) in Control and CriptoMy‐LOF TA sections at days 2 (top panel) and 5 (bottom panel) after injury.
  • B
    Quantification of F4/80 staining/damaged area (μm2) at days 2 (top graph) and 5 (bottom graph) after injury.
  • C
    Representative pictures of immunostaining for CD206 in Control and CriptoMy‐LOF TA sections at days 2 (top panel) and 5 (bottom panel) after injury, respectively.
  • D, E
    Quantification of CD206+ MPs per area (mm2) at days 2 (D) and 5 (E) after injury.
Data information: Nuclei were counterstained with DAPI (blue). Scale bar: 50 μm. Magnification of the boxes is 3.5×. Data are expressed as box plots displaying minimum, first quartile, median, third quartile, and maximum (n ≥ 5 biological replicates; **P < 0.01, Student's t‐test).