Figure 3. Injection of MSCs induces granulation tissue formation in CD18^−/− wounds.

1. Cryosections of PBS‐ or AT‐MSC‐injected CD18^−/− wounds at days 5 and 7 post‐wounding were immunostained for α‐SMA (red). Nuclei were stained with DAPI (blue). The dashed lines separate epidermis and wound bed. e, epidermis; wb, wound bed. Scale bars: 100 μm.
2. Quantification of α‐SMA immunofluorescence shown in (A), mean ± SEM, n = 3 wounds per group, *P < 0.05 by two‐tailed unpaired t‐test.
3. Cryosections of AT‐MSC‐injected CD18^−/− wounds at day 5 post‐wounding were co‐immunostained for human β2M (green) and TGF‐β1 (red, upper panel) or α‐SMA (red, lower panel). The depicted results are representative photographs of three independent experiments. Scale bars: 50 μm.

Source data are available online for this figure.