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. 2019 May 22;14(6):595–611. doi: 10.2217/rme-2018-0145

Table 2. . Properties of mesenchymal stromal cells with potential for potency assay development.

Indication Properties relevant to potency assay development Ref.
Multiple organ dysfunction syndrome IL-10 release [82]
Graft-vs-host disease TNF-R1 expression [83]
Multiple immune/inflammatory conditions T-cell proliferation suppression [49]
  CD4+ T-cell proliferation suppression [84]
  TNF-α inhibition [85]
Corneal damage from chemical insult TNF-α stimulated gene/protein 6 (TSG-6) expression [86]
Acute myocardial infarction In vitro tubule formation (CXCL5, IL-8, VEGF expression) [87]
Cartilage repair Receptor tyrosine kinase‐like orphan receptor 2 (ROR2) expression [88]