Table 1.
Demographic Characteristics of Patients Treated with Celyvir
| Pediatric Patients (n = 9) | Adult Patients (n = 7) | |
|---|---|---|
| Evaluable for toxicity | 9 | 7 |
| Evaluable for response | 9 | 6 |
| Age, years: median (range) | 7.5 (3.5–17.3) | 38.6 (25–66) |
| Performance Status (Lansky or Karnofsky for Children/ECOG for Adults) | ||
| 90–100/0–1 | 5 | 6 |
| 70–80/1–2 | 4 | 1 |
| Tumor Types | ||
| CNS tumors | 1 | 3 |
| Medulloblastoma | 1 | |
| Astrocytoma | 3 | |
| Non-CNS pediatric/adolescent tumors | 8 | 1 |
| Neuroblastoma | 4 | |
| Non-rhabdo soft-tissue sarcoma | 1 | |
| Ewing sarcoma | 1 | 1 |
| Rhabdomyosarcoma | 1 | |
| Osteosarcoma | 1 | |
| Non-CNS adult tumors | 4 | |
| Colorectal carcinoma | 1 | |
| Lung carcinoma | 1 | |
| Thyroid carcinoma | 1 | |
| Thymoma | 1 | |
| Prior Therapies | ||
| Chemotherapy | 8 | 7 |
| Surgery | 6 | 6 |
| Radiotherapy | 5 | 6 |
| Other (biological, immunological) | 0 | 0 |