Table 5.

Site-specific accuracy of the best-performing algorithms

Study sites	Sensitivity % (95% CI)	Specificity % (95% CI)	PPV % (95% CI)	NPV % (95% CI)
Panel A – Site-specific accuracy of the algorithm achieving the highest overall PPV (Algorithm 6)
UHC A	61.5 (54.3–68.7)	88.9 (85.3–92.4)	75.9 (68.8–83.0)	80.2 (75.9–84.4)
UHC B	78.7 (72.1–85.2)	85.9 (82.2–89.5)	70.7 (63.8–77.6)	90.3 (87.1–93.5)
Panel B – Site-specific accuracy of the algorithm achieving highest overall sensitivity (Algorithm 5)
UHC A	62.6 (55.5–69.8)	87.9 (84.2–91.5)	74.6 (67.6–81.7)	80.5 (76.2–84.7)
UHC B	79.3 (72.9–85.8)	84.4 (80.6–88.3)	68.8 (61.9–75.7)	90.4 (87.2–93.6)

Abbreviations: CI Confidence interval, PPV Positive predictive value, NPV Negative predictive value