Table 1.
Characteristics of the 40 patients submitted to percutaneous mitral commissurotomy, in the overall population and according to procedural success
| Whole population (N = 40) | Successful PMC (n = 30) | Unsuccessful PMC (n = 10) | pvalue | |
|---|---|---|---|---|
| Age, years | 63.5 ± 12.7 | 60.2 ± 12.8 | 68.2 ± 10.2 | 0.08 |
| Female sex | 32 (80) | 22 (73) | 10 (100) | 0.6 |
| NYHA class 3–4 | 23 (57.5) | 18 (60) | 5 (50) | 0.17 |
| Atrial fibrillation | 18 (45) | 12 (40) | 6 (60) | 0.46 |
| Previous mitral surgery or PMC | 7 (17.5) | 4 (13) | 7 (70) | 0.002 |
| Significant aortic stenosis | 6 (15) | 5 (17) | 1 (10) | 0.95 |
| Hypertension | 9 (22.5) | 5 (17) | 4 (40) | 0.95 |
| Renal failure (CrCl ≤60 ml/min) | 18 (45) | 12 (40) | 6 (60) | 0.46 |
| Obesity | 9 (22.5) | 7 (23) | 2 (20) | 0.81 |
| ACEI or ARB | 10 (25) | 7 (23) | 3 (30) | 0.98 |
| Beta blockers | 20 (50) | 13 (43) | 7 (70) | 0.26 |
| Diuretics | 25 (62.5) | 17 (57) | 8 (80) | 0.35 |
| Aldosterone antagonist | 8 (20) | 4 (13) | 4 (40) | 0.16 |
| Left atrial diameter, mm | 48 ± 7.1 | 46 ± 7.8 | 49 ± 6.9 | 0.28 |
| Left atrial area, cm2 | 32 ± 7.1 | 32 ± 37 | 47 ± 6.9 | < 0.0001 |
| Left atrial volume, mm3 | 129 ± 42 | 62 ± 20.5 | 185 ± 37 | < 0.0001 |
| Mitral valve gradient, mmHg | 9.1 ± 3.5 | 9.2 ± 3.5 | 8.7 ± 3.4 | 0.7 |
| Mitral valve area, cm2 | 1.1 ± 0.2 | 1.1 ± 0.2 | 1.1 ± 0.2 | 1 |
| LV end-diastolic diameter, mm | 49 ± 7.7 | 49 ± 7.9 | 46 ± 6.3 | 0.28 |
| LV end-systolic diameter, mm | 31 ± 4.6 | 31 ± 4.5 | 30 ± 5 | 0.55 |
| LVEF % | 64 ± 7.9 | 64 ± 8.1 | 64 ± 6.9 | 1 |
| sPAP, mmHg | 44 ± 14± | 46 ± 15 | 42 ± 7 | 0.42 |
| Mitral regurgitation ≥2 | 8 (20) | 6 (20) | 2 (20) | 0.65 |
| Wilkins score > 8 | 14 (35) | 9 (30) | 5 (50) | 0.44 |
PMC percutaneous mitral commissurotomy, NYHA New York Heart Association, CrCl creatinine clearance, ACEI angiotension-converting enzyme inhibitor, ARB angiotensin-receptor blocker, LVEF left ventricular ejection fraction, sPAP systolic pulmonary artery pressure