Table 3.
Laboratory values and iron therapy in cases and controls
| Laboratory measure | N case; N control | Case | Control |
|---|---|---|---|
| Ferritin measured in pregnancy – n (%) | 145; 145 | 101 (70) | 102 (70) |
| Ferritin measured in 1st trimester – n (%) | 145; 145 | 56 (39) | 56 (39) |
| Preconception iron deficiency – n (%) | 85; 41 | 27 (32) | 9 (22) |
| Ferritin < 30 μg/L – n (%) | 53; 23 | 26 (49) | 8 (35) |
| TSAT < 20% – n (%) | 2; 1 | 0 (0) | 0 (0) |
| MCV < 80 fL when previously normal– n (%) | 85; 40 | 2 (2) | 1 (3) |
| Preconception anemia – n (%) | 85; 40 | 15 (18) | 8 (20) |
| Iron deficiency in pregnancy – n (%) | 145; 145 | 72 (50) | 62 (43) |
| Ferritin < 30 μg/L – n (%) | 101; 102 | 64 (63) | 59 (58) |
| TSAT < 20% – n (%) | 2; 2 | 2 (100) | 2 (100) |
| MCV < 80 fL when previously normal – n (%) | 145; 131 | 8 (6) | 8 (6) |
| Anemia in pregnancy – n (%) | 145; 145 | 63 (44) | 23 (16) |
| Iron deficiency anemia in pregnancy – n (%) | 145; 145 | 32 (22) | 11 (8) |
| Lowest hemoglobin in pregnancy - median in g/L (IQR) | 145; 145 | 108 (14) | 117 (12) |
| Lowest ferritin in pregnancy – median in μg/L (IQR) | 101; 102 | 24 (24) | 27 (30) |
| Lowest MCV in pregnancy – median in fL (IQR) | 145; 145 | 87.6 (6.5) | 88.2 (5.9) |
| Postpartum iron deficiency – n (%) | 144; 75 | 14 (10) | 5 (7) |
| Ferritin < 30 μg/L – n (%) | 20; 7 | 7 (35) | 0 (0) |
| TSAT < 20% – n (%) | 1; 0 | 0 (0) | 0 (0) |
| MCV < 80 fL when previously normal – n (%) | 144; 74 | 7 (5) | 5 (7) |
| Postpartum anemia (Hb < 110 g/L up to 6 months)– n (%) | 144; 74 | 142 (99) | 39 (53) |
| Oral iron – n (%) | 145; 145 | 30 (42) | 23 (37) |
| Intravenous iron – n (%) | 145; 145 | 22 (15) | 3 (5) |
IQR interquartile range, MCV mean corpuscular volume, TSAT transferrin saturation