Figure 1.

Experimental design—serial visual reversal learning. (A) Timeline of the touchscreen serial visual reversal learning experiment (RL) involving behavioral training, surgery and behavioral testing with intracerebral infusions of baclofen/muscimol or vehicle. (B) Timeline of one of the two weeks of reversal learning testing with baclofen/muscimol or vehicle infusions. (C) Diagram of stimuli presented at different stages of pretraining (from stages 1 to 5). (D) Representation of the stimuli presented to the rats during the serial reversal learning training and testing (VD1). (E) Flowchart of possible trial sequences in the touchscreen visual discrimination and reversal learning task. CS, conditioned stimulus; ITI, inter-trial interval; VD, visual discrimination.