Figure 10.

Effects found in IN-specific Reelin knockout mice were not mimicked in heterozygous Reln^wt/dl animals. Analysis of Calretinin (A) and CB1 (B) immunoreactivity within the iML of Reln^wt/dl and Reln^wt/wt animals revealed comparable intensity levels in both genotypes. In addition, quantification of Reelin-expressing CR cells around the hippocampal fissure (yellow arrowheads) (C) showed a tendency to reduced numbers (not significant) and analysis of GFAP filaments (D) a tendency to increased levels (not significant) in Reln^wt/dl mice, compared with Reln^wt/wt (t-test; N = 4 animals; age: 24 weeks; error: ±SEM).