Table 1.
Information about the 20 experimentally confirmed circular bacteriocins and their producer strains. P denotes the characteristic is putative based on the shared characteristics with the other circular bacteriocins
| Class | Circular bacteriocin | Bacterial producer | 3D structure | α helices | aa size of mature peptide (Mass in Da) | Cluster location | Conjugative plasmid (Y/N/Unknown) | Genes in cluster | Translational coupling | Accession number | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|
| i | Aureocyclicin 4185 | Staphylococcus aureus 4185 | Model based on carnocyclin A | 4P | 60 (5607 Da) | pRJ101 | Unknown (data unavailable) | 11 | Y | KF836421 | [18] |
| i | Enterocin NKR-5-3B | Enterococcus faecium NKR-5-3B | NMR solution structure | 4 | 64 (6316.4 Da) | Unknown (data unavailable) | N | 5 | Y | LC068607 | [11] |
| i | Amylocyclicin | Bacillus amyloliquefaciens FZB42 | N/A | 4P | 64 (6382 Da) | Chromosome | N | 6 | Y | CP000560.1 | [19] |
| i | Amylocyclicin CMW1 | Bacillus amyloliquefaciens CMW1 | N/A | 4P | 64 (6351.59 Da) | Chromosome | N | 6 | Y | DF836085 | [20] |
| i | AS-48 | Enterococcus faecalis subsp. liquefaciens S-48 | NMR solution structure | 5 | 70 (7150.17 Da) | pMB2 | Y | 10 | Y | AJ438950.1 | [3] |
| i | bacA | Enterococcus faecalis 39–5 | N/A | 5P | 70 (7150.17 Da) | pPD1 | Y | 9 | Y | D85752 | [21] |
| i | Carnocyclin A | Carnobacterium maltaromaticum UAL307 | NMR | 4 | 60 (5862 Da) | Unknown (data unavailable) | Unknown (data unavailable) | 10 | Y | EU624394 | [22] |
| i | Circularin A | Clostridium beijerinckii ATCC 25752 | N/A | 5P | 69 (6789.05 Da) | Chromosome | N | 8 | Y | AJ566621.1 | [23] |
| i | Thermocin 458 | Geobacillus stearothermophilus DSM 458 | N/A | 5P | 70 (6933.25 Da) | Chromosome | N | 8 | Y | NZ_CP016552.1 | [24] |
| i | Garvicin ML | Lactococcus garvieae DCC43 | PSIPRED and Jpred3 model | 4P | 60 (6007.2 Da) | Chromosome | N | 8P | Y | NZ_AMQS01000001 | [25] |
| i | Lactocyclicin Q | Lactococcus sp. QU 12 | Model using PSIPRED | 4P | 61 (6062.8 Da) | Unknown (data unavailable) | Unknown (data unavailable) | Unknown (data unavailable) | Y | AB462499.1 | [26] |
| i | Leucocyclicin Q | Leuconostoc mesenteroides TK41401 | N/A | 4P | 61 (6133.23 Da) | Unknown (data unavailable) | Unknown (data unavailable) | 5 | Y | AB795997.1 | [27] |
| i | Pumilarin | Bacillus pumilus B4107 | N/A | 5P | 70 (7083.08 Da) | Chromosome | N | 5 | Y | NZ_AMDH01000012.1 | [28] |
| i | Uberolysin | Streptococcus uberis 42 | N/A | 5P | 70 (7043.94 Da) | Chromosome | N | 6P | Y | DQ650653 | [29] |
| ii | Acidocin B | Lactobacillus acidophilus M46 | NMR solution structure | 4 | 58 (5621.5 Da) | pCV461 | Unknown (data unavailable) | 7 | Y | KP728900.1 | [30] |
| ii | Butyrivibriocin AR10 | Butyrivibrio fibrisolvens AR10 | N/A | 4P | 58 (5981.5 Da) | Chromosome | N | 5 | Y | AF076529 | [31] |
| ii | Paracyclicin |
Lactobacillus. paracesei subsp. paracasei JCM 8130/ DSM 5622 |
N/A | 4P | 58 (5905.75 Da) | pLBPC-1 | Y | 7P | Y | NZ_AP012542.1 | [32] |
| ii |
Gassericin A/ Reutericin 6 |
Lactobacillus gasseri LA39/ Lactobacillus reuteri LA6 |
N/A | 4P | 58 (5653.6 Da) | pLgLA39 | Y | 7 | Y | AB436615.1 | [2] |
| ii | Plantacyclin B21AG | Lactobacillus plantarum B21 | N/A | 4P | 58 (5668 Da) | pB21AG01 | YP | 7 | Y | NZ_CP025732.1 | [33] |
| ii | Plantaricyclin A | Lactobacillus plantarum NI326 | N/A | 4P | 58 (5572 Da) | pB21AG01-like plasmid | YP | 7 | Y | NZ_NDXC01000075.1 | [4] |