Table 2.
List of circular bacteriocins identified with potential activity against clinically relevant isolates as part of the WHO’s Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics [44]
| Identified previously/in this study | Pathogen potentially susceptible | Bacteriocin producer | Experimental anti-bacterial activity against clinically relevant bacteria | Source |
|---|---|---|---|---|
| Identified previously | Enterococcus faecium | Enterococcus faecalis 39–5 | S. aureus, E. faecalis, E. faecium, S. agalactiae, S. sanguis | [45] |
| Enterococcus faecium | Enterococcus faecalis subsp. liquefaciens S-48 | S. faecalis S-47, Escherichia coli U-9, E. faecalis OGlX | [46, 47] | |
| Enterococcus faecium | Enterococcus faecium NKR-5-3B | B. coagulans, B. subtilis, L. lactis ssp. lactis, L. sakei ssp. sakei | [48] | |
| Staphylococcus aureus | Staphylococcus aureus 4185 | B. cereus, B. coagulans, B. licheniformis, L. monocytogenes, M. luteus | [49, 50] | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus uberis 42 | E. faecalis, E. hirae, M. luteus, S. aureus, S. agalactiae, S. salivarius, S. pyogenes, S. equisimilis, S. dysgalactiae, S. anginosus | [29] | |
| Identified in this study | Enterococcus faecium | Enterococcus villorum F1129D | N/A | This study |
| Enterococcus faecium | Enterococcus thailandicus a523 | N/A | This study | |
| Enterococcus faecium | Enterococcus faecium E8172 | N/A | This study | |
| Enterococcus faecium | Enterococcus faecium IHC105 | N/A | This study | |
| Enterococcus faecium | Enterococcus faecalis AZ19 | N/A | This study | |
| Staphylococcus aureus | Staphylococcus felis F9 | N/A | This study | |
| Staphylococcus aureus | Staphylococcus felis F21 | N/A | This study | |
| Staphylococcus aureus | Staphylococcus xylosus INIFAP 004–15 | N/A | This study | |
| Staphylococcus aureus | Staphylococcus kloosii SNUC 4696 | N/A | This study | |
| Staphylococcus aureus | Staphylococcus aureus 3688STDY6124959 | N/A | This study | |
| Staphylococcus aureus | Staphylococcus epidermidis AU23 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus uberis NCTC 4674 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus suis YS111 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus sp. OBRC6 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus gordonii BCA7 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus cristatus 787_SOLI | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus sp. CCH8-G7 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus mitis KCOM 1350 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus pneumoniae UoS2029 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus thermophilus NCTC 12958 | N/A | This study | |
| Streptococcus pneumoniae/Group A/Group B | Streptococcus pneumoniae Zo 18 m39–2 | N/A | This study |