Table 2.
Relationship between TFPI2 mRNA and clinico-pathological parameters
| Parameters | Number of patients | TFPI2 mRNA expression | P value | |
|---|---|---|---|---|
| Low (< median) | High (≥ median) | |||
| Number | 50 | 25 | 25 | |
| Age | ||||
| < Mean (47) | 27 | 14 | 13 | 0.777 |
| ≥ Mean (47) | 23 | 11 | 12 | |
| Tumor size | ||||
| T1–2 | 26 | 18 | 8 | 0.005* |
| T3–4 | 24 | 7 | 17 | |
| Nodal status | ||||
| N0–1 | 23 | 14 | 9 | 0.156 |
| N2–3 | 27 | 11 | 16 | |
| Metastasis | ||||
| M0 | 32 | 20 | 12 | 0.018* |
| M1 | 18 | 5 | 13 | |
| Pathological stage | ||||
| I-II | 29 | 19 | 10 | 0.010* |
| III-IV | 21 | 6 | 15 | |
*represents a significant relation between TFPI2 and clinico-pathological parameters of breast cancer patients