Table 2.
Risk of LVH or ESKD by ambulatory BP status in unadjusted and adjusted analyses
Ambulatory BP Classification (n=533) | LVH | ESKD | ||||
---|---|---|---|---|---|---|
Number of Events (n=62) | Unadjusted OR (95% CI) | Adjusted OR (95% CI)a | Number of Events (n=125) | Unadjusted HR (95% CI) | Adjusted HR (95% CI)a | |
Normotension (n=213)b | 14 | Reference | Reference | 41 | Reference | Reference |
Isolated BP load elevation (n=123)c | 15 | 2.0 (0.9 to 4.2) | 1.8 (0.8 to 4.2) | 26 | 1.1 (0.7 to 1.8) | 1.2 (0.7 to 2.0) |
Ambulatory Hypertension (n=197)d | 33 | 2.9 (1.5 to 5.5) | 2.8 (1.4 to 5.8) | 58 | 1.8 (1.2 to 2.7) | 1.3 (0.8 to 1.9) |
LVH, left ventricular hypertrophy; OR, odds ratio; HR, hazard ratio.
Adjusted for age, sex, race, cause of CKD, body mass index z-score, urine protein-creatinine ratio, antihypertensive use, and baseline eGFR (by bedside Schwartz), n=515 included due to missing covariates.
Normotension was defined as awake and asleep systolic BP or diastolic BP index <1.0 (e.g., mean ambulatory BP <95th percentile for sex and height), with awake and asleep systolic BP or diastolic BP load <25%.
Isolated BP load elevation was defined as awake and asleep systolic BP or diastolic BP index <1.0, with awake or sleep BP load ≥25%.
Ambulatory hypertension was defined as awake or asleep systolic BP or diastolic BP index ≥1.0, regardless of BP load.