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. 2020 Mar 11;15(4):493–500. doi: 10.2215/CJN.10130819

Table 2.

Risk of LVH or ESKD by ambulatory BP status in unadjusted and adjusted analyses

Ambulatory BP Classification (n=533) LVH ESKD
Number of Events (n=62) Unadjusted OR (95% CI) Adjusted OR (95% CI)a Number of Events (n=125) Unadjusted HR (95% CI) Adjusted HR (95% CI)a
Normotension (n=213)b 14 Reference Reference 41 Reference Reference
Isolated BP load elevation (n=123)c 15 2.0 (0.9 to 4.2) 1.8 (0.8 to 4.2) 26 1.1 (0.7 to 1.8) 1.2 (0.7 to 2.0)
Ambulatory Hypertension (n=197)d 33 2.9 (1.5 to 5.5) 2.8 (1.4 to 5.8) 58 1.8 (1.2 to 2.7) 1.3 (0.8 to 1.9)

LVH, left ventricular hypertrophy; OR, odds ratio; HR, hazard ratio.

a

Adjusted for age, sex, race, cause of CKD, body mass index z-score, urine protein-creatinine ratio, antihypertensive use, and baseline eGFR (by bedside Schwartz), n=515 included due to missing covariates.

b

Normotension was defined as awake and asleep systolic BP or diastolic BP index <1.0 (e.g., mean ambulatory BP <95th percentile for sex and height), with awake and asleep systolic BP or diastolic BP load <25%.

c

Isolated BP load elevation was defined as awake and asleep systolic BP or diastolic BP index <1.0, with awake or sleep BP load ≥25%.

d

Ambulatory hypertension was defined as awake or asleep systolic BP or diastolic BP index ≥1.0, regardless of BP load.