Table 1.
Gensini score quartiles |
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Characteristics | Total(n = 1326) | First quartile(n = 340) | Second quartile (n = 337) | Third quartile (n = 319) | Fourth quartile (n = 330) | P value |
Age, years | 58.5 ± 10.3 | 55.7 ± 9.5 | 59.0 ± 9.9 | 59.6 ± 10.4 | 60.0 ± 10.8 | <0.001 |
Sex | <0.001 | |||||
Male | 927 (69.9) | 187 (55.0) | 237 (70.3) | 231 (72.4) | 272 (82.4) | – |
Female | 399 (30.1) | 153 (45.0) | 100 (29.7) | 88 (27.6) | 58 (17.6) | – |
Current smoking | 590 (44.5) | 117 (34.4) | 159 (47.2) | 156 (48.9) | 158 (47.9) | <0.001 |
Diabetes mellitus | 211 (15.9) | 14 (4.1) | 46 (13.6) | 77 (24.1) | 74 (22.4) | <0.001 |
Hypertension | 681 (51.4) | 155 (45.6) | 171 (50.7) | 189 (59.2) | 166 (50.3) | 0.005 |
Hyperlipidaemia | 154 (11.6) | 31 (9.1) | 48 (14.2) | 39 (12.2) | 36 (10.9) | 0.203 |
Family history of CAD | 394 (29.7) | 105 (30.9) | 92 (27.3) | 110 (34.5) | 87 (26.4) | 0.093 |
Baseline SBP, mmHg | 134.8 ± 20.5 | 134.2 ± 18.8 | 135.7 ± 18.4 | 135.1 ± 21.9 | 134.3 ± 22.8 | 0.763 |
Baseline DBP, mmHg | 78.1 ± 11.8 | 77.5 ± 11.0 | 78.8 ± 11.9 | 77.9 ± 11.9 | 78.3 ± 12.4 | 0.482 |
Heart rate, bpm | 75.5 ± 13.7 | 74.5 ± 15.2 | 74.9 ± 12.5 | 75.6 ± 13.1 | 75.5 ± 13.7 | 0.102 |
RBCs, 1012/L | 4.8 ± 4.3 | 4.9 ± 3.0 | 4.6 ± 3.2 | 4.9 ± 3.6 | 5.0 ± 6.3 | 0.688 |
Hb, g/L | 134.4 ± 15.9 | 132.6 ± 15.4 | 134.5 ± 16.5 | 135.3 ± 15.9 | 135.3 ± 15.9 | 0.101 |
RDW, fl | 45.0 ± 4.4 | 44.5 ± 3.8 | 44.7 ± 3.5 | 45.1 ± 4.9 | 45.6 ± 5.0 | 0.007 |
MCV, fl | 93.2 ± 6.2 | 92.6 ± 6.2 | 92.8 ± 5.1 | 93.2 ± 6.4 | 94.1 ± 6.7 | 0.010 |
HCT, % | 40.2 ± 4.4 | 39.8 ± 4.2 | 40.3 ± 4.5 | 40.5 ± 4.4 | 40.4 ± 4.4 | 0.142 |
TC, mmol/L | 1.8 ± 1.2 | 1.7 ± 1.1 | 1.8 ± 1.0 | 1.7 ± 0.9 | 1.9 ± 1.7 | 0.431 |
HDL, mmol/L | 1.1 ± 0.3 | 1.2 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.3 | 0.003 |
LDL, mmol/L | 2.7 ± 0.9 | 2.7 ± 0.8 | 2.7 ± 0.9 | 2.6 ± 0.9 | 2.7 ± 1.0 | 0.912 |
VLDL, mmol/L | 0.6 ± 0.4 | 0.6 ± 0.4 | 0.6 ± 0.4 | 0.5 ± 0.4 | 0.6 ± 0.5 | 0.691 |
Results are presented as mean ± standard deviation or n (%). The P values represent the difference among the four quartiles.
First quartile, ≤5 points; second quartile, 6–20 points; third quartile, 21–48 points; fourth quartile, ≥49 points.
CAD, coronary artery disease; DBP, diastolic blood pressure; Hb, haemoglobin; HCT, haematocrit; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MCV, mean corpuscular volume; RBCs, red blood cells; RDW, red blood cell distribution width; SBP, systolic blood pressure; TC, total cholesterol; VLDL, very-low-density lipoprotein.