Table 2.

Veterans Aging Cohort Study Index 2.0 Cox Proportional Hazards Model, for 5-Year All-Cause Mortality, Estimated in Veterans Aging Cohort Study

n	28,390
Deaths	7,293
Parameter	PE	SE	χ2	p	HR	95% CI
Age (years), censored at 30–75, centered at (age—50)
X	0.056	0.012	22	<.0001	1.06	0.00–0.00
X2	−0.004	0.004	2	.22	1.00	0.00–0.00
X3	0.005	0.001	29	<.0001	1.01	0.00–0.00
CD4 cell count (cells/mL), censored at 0–1,000, as ln (1,000-CD4)
X	−0.056	0.025	5	.03	0.95	0.00–0.00
X2	−0.153	0.023	46	<.0001	0.86	0.00–0.00
X3	0.024	0.002	94	<.0001	1.02	0.00–0.00
HIV-1 RNA (log copies/mL), censored at 1.3–5.0, centered at (logVL—2)
X	0.513	0.033	247	<.0001	1.67	0.00–0.00
X2	−0.422	0.041	109	<.0001	0.66	0.00–0.00
X3	0.098	0.011	77	<.0001	1.10	0.00–0.00
Hemoglobin (g/dL), censored at 9–16, centered at (14—hemoglobin)
X	−0.134	0.011	141	<.0001	0.88	0.00–0.00
X2	0.026	0.006	16	<.0001	1.03	0.00–0.00
X3	0.005	0.001	10	.002	1.01	0.00–0.00
FIB-4, censored at 0.5–7.5
X	0.220	0.028	62	<.0001	1.25	0.00–0.00
X2	−0.009	0.003	7	.008	0.99	0.00–0.00
eGFR (mL/min), censored at 0–180a
X1	−0.031	0.028	1	.28	0.97	0.00–0.00
X2	−0.077	0.045	3	.0917	0.93	0.00–0.00
X3	0.106	0.027	16	<.0001	1.11	0.00–0.00
X4	0.133	0.034	15	.0001	1.14	0.00–0.00
Hepatitis C coinfection
Yes	0.342	0.028	147	<.0001	1.41	0.00–0.00
Albumin (g/dL), censored at 2–5, centered at (albumin—4)
X	−0.443	0.034	165	<.0001	0.64	0.00–0.00
X2	0.104	0.051	4	.04	1.11	0.00–0.00
X3	0.028	0.027	1	.30	1.03	0.00–0.00
White blood count (k/mL), censored at 2.5–11, centered at (WBC—5.5)
X	0.126	0.011	130	<.0001	1.13	0.00–0.00
X2	0.020	0.004	30	<.0001	1.02	0.00–0.00
X3	−0.004	0.001	23	<.0001	1.00	0.00–0.00
BMI, kg/m2, censored at 15–35, centered at (BMI—25)
X	−0.055	0.003	388	<.0001	0.95	0.00–0.00
X2	0.004	0.000	62	<.0001	1.00	0.00–0.00

^aX1 = eGFR/10, X2 = (eGFR-35)/10, X3 = (eGFR-65)/10, X4 = (eGFR-115)/10.

BMI, body mass index; CI, confidence interval; HR, hazard ratio; PE, parameter estimate; SE, standard error; WBC, white blood cell.