Methods |
Randomised controlled trial |
Participants |
598 trauma patients >16 years of age with penetrating injuries and hypotension
Mean age = 31 years
Exclusion: pregnancy, Revised Trauma Score = 0, minor injuries not requiring surgery |
Interventions |
1) 870ml of Ringer's solution pre‐hospital (n=309)
2) 92ml of Ringer's solution with IV cannulation pre‐hospital (n=289) |
Outcomes |
|
Notes |
Patients in both groups were treated with a standard paramedical protocol as appropriate until after IV cannulation.
22/289(8%) in delayed fluids group were inadvertently given fluids in violation of the protocol. Results were analysed as randomised on an intention‐to‐treat basis. |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Allocation concealment (selection bias) |
High risk |
Allocation by alternation ‐ odd and even numbered days of the month |