Skip to main content
. 2014 Mar 5;2014(3):CD002245. doi: 10.1002/14651858.CD002245.pub2

Bickell 1994.

Methods Randomised controlled trial
Participants 598 trauma patients >16 years of age with penetrating injuries and hypotension
 Mean age = 31 years
 Exclusion: pregnancy, Revised Trauma Score = 0, minor injuries not requiring surgery
Interventions 1) 870ml of Ringer's solution pre‐hospital (n=309)
 2) 92ml of Ringer's solution with IV cannulation pre‐hospital (n=289)
Outcomes
  • haemodynamic variables

  • amount of fluids given

  • intra‐operative blood loss

  • post‐operative

  • complications

  • process of care

  • death

Notes Patients in both groups were treated with a standard paramedical protocol as appropriate until after IV cannulation.
 22/289(8%) in delayed fluids group were inadvertently given fluids in violation of the protocol. Results were analysed as randomised on an intention‐to‐treat basis.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) High risk Allocation by alternation ‐ odd and even numbered days of the month