| Methods |
Randomised controlled trial |
| Participants |
25 patients with acute injury and haemorrhage, hypotensive, urine output < 20ml/hr
Mean age = 46
Exclusion: history of myocardial infarction in previous year as a higher haematocrit could be harmful |
| Interventions |
≥ 5 units of blood to maintain Haematocrit at 40% (n=13) < 5 units of blood transfusion to maintain haematocrit at 30% (n=12) |
| Outcomes |
|
| Notes |
Study was designed to test the hypothesis that sufficient oxygen can be provided at lower haematocrit of 30%.
Allocation concealment was later reported to be adequate when co‐author was contacted. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
Quote: 'Random allocations generated by a statistician blinded to the study, in sets of sealed opaque envelopes.' (Direct contact with the study author) |
