. 2013 Jan 31;2013(1):CD002808. doi: 10.1002/14651858.CD002808.pub3

Librati 1996.

Methods	Generation the allocation sequence: not reported Allocation concealment method: not reported   Blinding method: not reported   Power calculation: not reported   Number and reasons for withdrawals: withdrawals reported as exclusion criteria   Intention‐to‐treat analysis: no
Participants	Group A (Depot) leuprolide 3.75 mg SC administered on first day of menses: 85 participants, and Group B (Daily) Decapeptyl 0.1 mg/day SC administered on first day of menses, and continued until the day of human chorionic gonadotrophin (hCG) administration: 75 participants
Interventions	Ovarian stimulation started 14 days after menses with hCG or FSH 4 ampoules (300 IU) during the first 2 days, 3 ampoules for the next 3 days, and adjusting the dose on the consecutive days
Outcomes	Primary outcome: not reported (reported pregnancy rate per transfer) Secondary outcomes: number of oocytes retrieved per woman; miscarriage rate per pregnancy; number of gonadotropin (FSH) units employed per cycle
Notes	Setting of the study: Bordeaux, France   Statistical tests: the Chi² test and Fisher Student test were used to compare variables
*Risk of bias*
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method not reported
Allocation concealment (selection bias)	Unclear risk	Method not reported
Blinding (performance bias and detection bias)   All outcomes	Low risk	Blinding not reported but unlikely to influence primary review outcomes
Incomplete outcome data (attrition bias)   All outcomes	High risk	180 women randomised, 20 of whom withdrew. The only reason given by the author was that the participants did not obtain at least 1 embryo for transfer. This is considered exclusion and not withdrawal.
Selective reporting (reporting bias)	Unclear risk	Did not report live births/ongoing pregnancy or OHSS
Other bias	High risk	The author does not report means and standard deviations, nor the standard errors. The author presents the results only in percentages, making it difficult to know the exact number of occurrences.