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. 2020 Mar 27;11:206. doi: 10.3389/fneur.2020.00206

Table 1.

Demographic differences between the set for developing criteria and the set for validation.

The set for developing selection criteria (N = 1,860) The set for validation (N = 798) p
Age 65.5 ± 11.1 64.7 ± 11.2 0.078
Sex, male 1214 (65.3) 531 (66.5) 0.568
CAC score* 70.55 (3.05-293.45) 56.55 (3.68-245.40) 0.099
CAC group 0.409
  CAC score 0 346 (18.6) 139 (17.4)
  0 < CAC score <100 698 (37.5) 327 (41.0)
  100 ≤ CAC score <400 457 (24.6) 183 (22.9)
  CAC score ≥ 400 359 (19.3) 149 (18.7)
Severe coronary artery disease 256 (13.8) 104 (13.0) 0.658
Risk factors
  Hypertension 1416 (76.1) 607 (76.1) 1
  Diabetes mellitus 612 (32.9) 262 (32.8) 1
  Dyslipidemia 247 (13.3) 92 (11.5) 0.239
  Smoking 491 (26.4) 234 (29.3) 0.132
  Metabolic syndrome 786 (42.3) 347 (43.5) 0.587
  Atrial fibrillation 242 (13.0) 97 (12.2) 0.587
Laboratory findings
  Total cholesterol 183.4 ± 61.5 182.7 ± 64.9 0.807
  Triglyceride 129.1 ± 95.0 127.2 ± 84.2 0.618
  HDL cholesterol 42.3 ± 10.6 42.2 ± 11.1 0.759
  LDL cholesterol 108.7 ± 35.4 107.9 ± 35.8 0.631
  HbA1c 6.7 ± 3.5 6.5 ± 1.4 0.051
  CRP 13.2 ± 32.0 11.5 ± 29.8 0.442
  hs-CRP 6.9 ± 18.8 6.6 ± 21.6 0.741
  Initial glucose 142.7 ± 62.5 140.7 ± 56.3 0.421
  Fasting glucose 115.6 ± 41.5 116.9 ± 70.1 0.621
Initial systolic BP 155.7 ± 39.7 155.6 ± 31.0 0.903
Initial diastolic BP 85.6 ± 15.5 86.6 ± 16.3 0.161
Previous cerebral infarction 250 (13.4) 113 (14.2) 0.665
Peripheral artery disease 45 (2.4) 13 (1.6) 0.257

Values are presented as the mean ± standard deviation or number (%), except CAC score*.

CAC scores* are presented as the median (interquartile range).

BP, blood pressure; CAC, coronary artery calcium; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein.