Table 3.

Association between severe coronary artery disease and clinical factors.

	Univariate analysis		Multivariate analysis*		Multivariate analysis†
	Odds ratio (95% CI)	P	Odds ratio (95% CI)	P	Odds ratio (95% CI)	P
Age	1.05 (1.04–1.06)	<0.0001	1.06 (1.04 −1.07)	<0.0001
Age (>65)	2.45 (1.83–3.28)	<0.0001			2.62 (1.93–3.55)	<0.0001
Sex (male)	1.59 (1.18–2.14)	0.002	1.95 (1.42–2.67)	<0.0001	1.81 (1.33–2.46)	<0.0001
Risk factors
Hypertension	1.6 (1.14–2.26)	0.007	1.32 (0.92–1.88)	0.134	1.40 (0.98–2.00)	0.062
Diabetes mellitus	1.39 (1.06–1.83)	0.017	1.09 (0.78–1.50)	0.623	1.21 (0.89–1.66)	0.232
Dyslipidemia	1.68 (1.19–2.37)	0.003	1.81 (1.25–2.61)	0.002	1.77 (1.25–2.61)	0.002
Smoking	1.11 (0.82–1.49)	0.5
Metabolic syndrome	0.96 (0.74–1.26)	0.766
Peripheral artery disease	3.62 (1.94–6.77)	<0.0001	2.32 (1.19–4.51)	0.014	2.64 (1.37–5.06)	0.004
Previous cerebral infarction	1.6 (1.13–2.27)	0.008	1.39 (0.97–2.00)	0.073	1.32 (0.92–2.53)	0.133
Laboratory findings
HbA1c	1.00 (0.95–1.04)	0.845
Initial glucose	1.00 (1.00–1.00)	0.137
Fasting glucose	1.00 (1.00–1.00)	0.008	1.01 (1.00–1.01)	0.008
Fasting glucose (>113mg/dl)	1.32 (1.01–1.73)	0.04			1.19 (0.88–1.62)	0.26
C-reactive protein	1.01 (1.00–1.01)	0.296
hs-CRP	1.00 (1.00–1.01)	0.479
Total cholesterol	1.00 (1.00–1.00)	0.703
Triglyceride	1.00 (1.00–1.00)	0.941
HDL cholesterol	0.99 (0.97–1.00)	0.029	0.99 (0.98–1.01)	0.331
HDL cholesterol (≤ 41mg/dl)	1.34 (1.03–1.75)	0.031			1.23 (0.93–1.62)	0.144
LDL cholesterol	1.00 (1.00–1.01)	0.427

^*Was performed with age, levels of laboratory findings as continuous covariates.

^†Was performed with age, fasting glucose, and HDL cholesterol as categorical covariates.

CI, confidence interval; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein.