Table 4.
Association between cerebral atherosclerosis and severe coronary artery disease.
| Univariate analysis | Multivariate analysis* | Multivariate analysis† | |||||
|---|---|---|---|---|---|---|---|
| Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | Odds ratio (95% CI) | P | ||
| ACA | <50 | Reference | |||||
| ≥50 | 1.69 (0.94–3.03) | 0.079 | |||||
| MCA | <50 | Reference | |||||
| ≥50 | 1.33 (0.898–1.80) | 0.07 | |||||
| PCA | <50 | Reference | |||||
| ≥50 | 1.41(0.96–2.05) | 0.078 | |||||
| ICA | <50 | Reference | Reference | Reference | |||
| ≥50 | 3.05 (2.26–4.11) | <0.0001 | 2.87 (2.12–3.88) | <0.0001 | 2.79 (2.06–3.78) | <0.0001 | |
| BA | <50 | Reference | Reference | ||||
| ≥50 | 1.96 (1.15–3.34) | 0.013 | 1.80 (1.05–3.09) | 0.033 | |||
| VA | <50 | Reference | Reference | ||||
| ≥50 | 2.11 (1.58–2.81) | <0.0001 | 1.90 (1.41–2.54) | <0.0001 | |||
| VBA | <50 | Reference | Reference | ||||
| ≥50 | 2.30 (1.74–3.04) | <0.0001 | 2.08 (1.57–2.76) | <0.0001 | |||
| Number of arteries with significant stenosis | |||||||
| Intracranial branches | 0 | Reference | |||||
| 1 | 1.41 (1.06–1.88) | 0.019 | |||||
| 2 | 1.52 (0.82–2.83) | 0.187 | |||||
| 3 | 3.06 (0.78–11.94) | 0.108 | |||||
| Cervicocephalic branches | 0 | Reference | |||||
| 1 | 2.31 (1.74–3.08) | <0.0001 | |||||
| 2 | 5.43 (3.42–8.61) | <0.0001 | |||||
*
was performed with BA and VA as separate covariates.
†
was performed with VBA as a covariate.
ACA, anterior cerebral artery; BA, basilar artery; CAC, coronary artery calcium; CI, confidence interval; ICA, internal carotid artery; MCA, middle cerebral artery; PCA, posterior cerebral artery; VA, vertebral artery; VBA, vertebrobasilar artery.