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The ChemoFilter (CF) device reduces accumulation of doxorubicin (DOX) in off-target organs. Bar graph shows mean DOX concentrations in organs in groups 1 (IAC + IAC) and 2 (IAC + IAC with CF). Significant decreases in DOX accumulation were observed in all off-target organs (kidneys and heart) in animals treated with CF devices compared with control animals. Data are mean ± standard deviation.
