Fig 8. Chronic smoke-induced weight loss is associated with reduced expression of the Alistipes genus in the cecal content.

A) Relative abundance of the bacterial genus Alistipes in mice stratified by smoke exposure and sex at 24 weeks post cigarette smoke exposure; p-value* was obtained using the Kruskal-Wallis test, and the Benjamini-Hochberg method was applied to compute adjusted p-values for multiple pairwise comparisons. Correlations between whole-body weight and the cecal relative abundance of Alistipes (%) are shown in male (B), female (C), and ovariectomized female (D) mice. Linear regression analyses were used in panels B-D. Red dot = control mice, blue dot = smoke-exposed mice. C = control, S = smoke-exposed, Ov Female = ovariectomized female.