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. 2020 Apr 2;13:2783–2793. doi: 10.2147/OTT.S232769

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© 2020 Ye et al.

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lncRNA SPRY4-IT1 expression is downregulated in A549/DDP cells.

Notes: (A) IC50 of cisplatin were detected in A549 and A549/DDP cells. (B) Morphologies of A549 and A549/DDP cells under microscope (40×magnification). (C) SPRY4-IT1 expression was significantly downregulated in A549/DDP cells compared with A549 cells. (D) A549/DDP cells were transfected with pCDNA-SPRY4-IT1 and pCDNA-NC. (E) IC50 of cisplatin were detected in A549/DDP cells transfected with pCDNA-SPRY4-IT1 and pCDNA-NC individually. **P<0.01.

Abbreviations: lncRNA, long noncoding RNA; SPRY4-IT1, SPRY4 intronic transcript 1; IC50, half-maximal inhibitory concentration; RT-qPCR, quantitative real-time polymerase chain reaction.