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. 2020 Apr 2;13:2783–2793. doi: 10.2147/OTT.S232769

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© 2020 Ye et al.

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MPZL-1 was down regulated by SPRY4-IT1.

Notes: (A) RNA transcriptome sequencing was used to detect the dysregulated genes after SPRY4-IT1 overexpression 24 h. (B) Gene Ontology (GO) enrichment analysis. (C) Ten up-regulated and ten down-regulated genes were identified by RNA transcriptome sequencing. (D) MPZL-1 was verified by qRT-PCR to be the target of SPRY4-IT1. (E) MPZL-1 was verified by Western blot to be the target of SPRY4-IT1.

Abbreviations: GO, Gene Ontology; SPRY4-IT1, SPRY4 intronic transcript 1; RT-qPCR, quantitative real-time polymerase chain reaction.