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(A) The blood circulation time of free PTX and IR-AFN@PTX-FA in healthy mice. (B) The content of IR-AFN@PTX and IR-AFN@PTX-FA in tumor tissue at different time points post-injection. (C) The content of IR-AFN@PTX and IR-AFN@PTX-FA in major organs including heart, liver, spleen, lung and kidney at 24 h post-injection.
Abbreviations: IR, IR1061; AFN, apoferritin; PTX, paclitaxel; FA, folic acid.
