Table 4.

Biologic agents and suggested treatments

Biologic agents	Suggested treatments	Prophylaxis
Botulinism	Antitoxin, supportive
Anthrax	Ciprofloxina, doxycylcineb, or penicillinc with streptomycind	Ciprofloxin or doxycline
		Anthrax vaccined
Tularemia	Streptomycin or gentamicin	Doxycycline or tetracycline
Plague	Streptomycin or gentamicin; doxycyline or chloramphenicol	Doxycycline or tetracycline
Smallpox	Cidovire	Smallpox vaccination within 4 days of exposure
Viral hemorrhagic fever	Ribavarinf

^aCiprofloxin is not approved by the Food and Drugs Administration for children less than 18 years of age.

^bDoxycycline and other tetracyclines are not recommended for childen less than 8 years of age but are indicated for serious infections.

^cPenicillin should be used for treatment only if the organism is known to be susceptible.

^dVaccine is not FDA approved and has only been used in persons 18 years and older.

^eCidovir has never been used in smallpox treatment but has been used in monkeypox treatment in adults.

^fRibavarin is effective for arenavirus or bunyavirus but not filovirus or flavovirus and is not FDA approved for children.